Good Clinical Practice (GCP) Practice Exam

In a double-blind study, both the participants and researchers are unaware of the treatment assignment. This design is critical in minimizing bias and ensuring that neither the expectations of the treatment staff nor the participants influence the outcomes of the study.

When researchers do not know which participants are receiving which treatment, it helps to prevent any conscious or unconscious bias in how they conduct assessments, interact with participants, or interpret results. Similarly, when participants are not aware of their treatment assignment, they are less likely to have their expectations influence their responses or perceived effects of the treatment. This dual blinding is essential to maintain the integrity of the data and the validity of the study’s conclusions.

Other options focus on only one group or incorrectly identify who remains informed about the treatment assignment. However, the strength of a double-blind study lies in its comprehensive approach to blinding.